Comparative study of the hypoglycemic and biochemical effects of Catharanthus roseus (Linn) G. apocynaceae (Madagascar periwinkle) and chlorpropamide (diabinese) on alloxan-induced diabetic rats.

The effect of the aqueous extracts of Catharanthus roseus and chlorpropamide (Diabenese) on the levels of serum cholesterol, total protein, lipid peroxidation, blood glucose and liver enzymes were compared in alloxan-induced diabetic rats. Four groups namely A, B, C and D comprising of nine rats each were used. A and B were administered with chlorpropamide and C. roseus extracts…