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Antioxidant phenolics from Broussonetia papyrifera fruits

Fractionation of the EtOH extract from the fruits of Broussonetia papyrifera led to the isolation of 15 phenolic compounds (1-15). Their structures were identified using spectroscopic methods. Among these compounds, 1 and 2 are new and 3-15 were isolated from this plant for the first time. Antioxidant activities of compounds 2-15 against H2O2-induced injury in

Toxicological evaluation of precocene II isolated from Ageratum conyzoides L. (Asteraceae) in Sprague Dawley rats

Precocene II (6,7-dimethoxy-2,2-dimethyl-2-chromene) was the main constituent isolated from Ageratum conyzoides L. and reportedly possessed antifungal activity. The study investigated the isolation, purification and toxicological effects of precocene II from A. conyzoides in Sprague Dawley rats. Precocene II was isolated from the petroleum ether fraction of the plant and the structure was…

An Antisalmonella agent and Dihydroanthracenone from Cassia petersiana

Phytochemical and biological investigation of the leaves of Cassia petersiana afforded four compounds including a new dihydroanthracenone (1), two known chromones (2,3), in addition to stigmasterol glucoside (4). The work was guided by the antisalmonellal activity of the extract and fractions. Compound 4 was found to be the active principle. The structures of the compounds

Effects of Ethanolic Fruit Extract of Parinari polyandra (Rosaceae) on serum Lipid Profile and some Electrolytes in Pregnant Rabbits

The effects of the ethanolic fruit extract of Parinari polyandra on lipid profile and electrolyte levels in pregnant rabbits were investigated. Graded concentrations of 0, 10, 50 and 250 mg kg-1 body weight of the extracts were administered by gastric intubations for a period of 14 days from the 12th -25th day of gestation after

Some lysosomal enzyme profiles in children with nephroblastoma: The effect of nephrectomy.

The serum levels of some lysosomal enzymes-namely β-glucuronidase (EC 3.2.1.31), β-galactosidase (EC 3.2.1.23) and acid phosphatase (EC 3.1.3.2)-were measured in controls, pre-operative and post-operative nephroblastoma patients. β-glucuronidase activity showed a significant (p<0.05) increase before surgical intervention, followed by significant (p<0.05) decreases 24 h, 72 h and 7 days after…

Nutritional Qualities of Three Medicinal Plant Parts (Xylopia aethiopica, Blighia sapida and Parinari polyandra) commonly used by Pregnant Women in the Western Part of Nigeria

The nutritional potentials of three medicinal plant parts used by pregnant women in the western part of Nigeria Parinari polyandra, Blighia sapida and Xylopia aethiopica were evaluated through their proximate compositions as well as percentage mineral elements composition. Blighia sapida was high in crude fibre (44.09±2.20%) compared with Parinari polyandra and Xylopia aethiopica that were…

Oxyphyllones A and B, novel sesquiterpenes with an unusual 4,5-secoeudesmane skeleton from Alpinia oxyphylla

Two novel 4,5-secoeudesmane sesquiterpenoids, oxyphyllones A (1) and B (2) were isolated from the fruits of Alpinia oxyphylla. Their structures were established by spectroscopic methods including 1D and 2D NMR spectra. These two compounds are the first example of naturally occurring sesquiterpenoids with a 4,5-secoeudesmane skeleton in the family of Zingiberaceae and oxyphyllone A (1)

A new norlignan from Taxodium ascendens

A new norlignan, (2R,3R,4S,5S)-2,4-bis(4-hydroxyphenyl)-3,5-dihydroxy-tetrahydropyran (1),together with 9 known compounds were isolated from the branches and leaves of Taxodium ascendens. Their structures were mainly determined on the basis of MS, IR, 1D and 2D NMR spectral evidences. Methanol extract showed inhibitory activity on carbonic anhydrase II with an IC50 value of 4.27 μg/ml, acetone…

The Effects of Ethanolic Leaf Extract of Commiphora africana (Burseraceae) on Rat Liver and Kidney Functions

The effects of Commiphora africana ethanolic leaf extract on some biochemical markers of liver and kidney functions were investigated in rats. The results showed a significant (p<0.05) decrease in serum albumin after 10 days of treatment for the group administered 100 mg kg-1 body weight of the extract. There was no significant (p>0.05) change in