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In vitro and in vivo antioxidant activities of the leaves of Chrysophyllum albidum

Chrysophyllum albidum G. Don. (Sapotaceae) which is distributed in Nigeria is used for the treatment of yellow fever, malaria, diarrhea, vaginal disorders, etc [1]. The study was aimed at investigating the antioxidant properties using in vitro and in vivo models. The effect of 1,1-diphenyl-2-picrylhydrazyl (DPPH) antiradical activity on ethanol, petroleum ether, ethylacetate, butanol, and water…

Antioxidant activities of the leaves of Chrysophyllum albidum G.

Chrysophyllum albidum G. is a tropical plant and commonly found in Nigeria. It belongs to the sapotaceae family and used in folklore in the treatment of yellow fever, malaria, diarrhea, vaginal and dermatological infections. The study was aimed at investigating the antioxidant properties of this plant by employing the in vitro and in vivo experimental

A New Chromene Isolated from Ageratum conyzoides L.

From the ethanol extract of the whole plant of Ageratum conyzoides L. (Compositae), one new chromene, 2,2-dimethylchromene 7-methoxy-6-O-β-D-glucopyranoside, was isolated, together with thirteen known compounds, seven of which were being reported for the first time. The compounds were all characterized by MS, IR, 1D- and 2D-NMR spectroscopy. 7,3′,5′-tri-O-methyltricetin (7), precocene II (9),…

Hepatoprotective activity of Chrysophyllum albidum against carbon tetrachloride induced hepatic damage in rats.

The leaf extract of Chrysophyllum albidum was studied for hepatoprotective activity against rats with induced liver damage by carbon tetrachloride (CCl4). The rats were divided into five groups of eight rats per group. Animals of group A served as normal and were given only vehicle (distilled water) for 7 days. Animals of group B (positive

Biochemical, haematological and histopathological studies of extract of Ageratum conyzoides L. in Sprague Dawley rats

This study was conducted to evaluate the safety potential of the leaf extract of Ageratum conyzoides Linnaeus in Sprague Dawley (SD) rats using biochemical, haematological and histological indices of toxicity. Four groups of seven male SD rats per group were used for the study. To group A was administered 0.25% CMC-Na/ kg body weight and

“Medicinal Plant” – Phytochemical and Biological Studies of Ageratum conyzoides Linnaeus

Ageratum conyzoides is a member of the family of “Asteraceace” and it is increasingly being used in traditional medicine for the treatment of diverse ailments. The book contains an indepth review of literature on medicinal plants. It also reported studies on the purification, isolation and characterization of active phytochemicals from Ageratum conyzoides. Antioxidant, anti-cancer, anti-…

Bioactive compounds from Rumex plants

Two new naphthalene acyl glucosides,rumex neposides A(1)and B(2), together with 12 known compounds (3-14), were isolated from the roots of Rumex nepalensis. Their structures were established by chemical and spectroscopic methods. The biological activities of compounds 1-14 as well as an additional 11 compounds previously isolated from R. nepalensis and Rumex hastatus (15–25) were evaluated…

Anticancer and antiradical scavenging activity of Ageratum conyzoides L. (Asteraceae)

Ageratum conyzoides has been used in folklore for the treatment of a wide range of diseases. In the present investigation, the in vitro activity of ethanol, petroleum ether, ethylacetate, butanol, and water extracts of A. conyzoides were screened in some cancer cell lines using the sulphorhodamine B (SRB) assay. These cell lines include: Human non-small

Effects of ethanolic leaf extract of Chrysophyllum albidum onG. on biochemical and haematological parameters of albino Wistar rats

The effect of oral administration of the leaf extract of Chrysophyllum albidum G. on biochemical and haematological parameters were investigated in albino rats for 16 days. The extract did not show any significant effect (p > 0.05) on the plasma concentrations of total bilirubin, albumin and alkaline phosphatase (ALP) as well as the packed cell